Osoyoos (, historically ) is the southern-most town in the Okanagan Valley in British Columbia between Penticton and Omak. Near the border with Washington state, the town is also adjacent to the Indian Reserve of the Osoyoos Indian Band. The origin of the name Osoyoos was the word sẁiẁs (pronounced "soo-yoos") meaning "narrowing of the waters" in the local Okanagan language (Syilx'tsn). The "O-" prefix is not indigenous in origin and was attached by settler-promoters wanting to harmonize the name with other place names beginning with O in the Okanagan region (Oliver, Omak, Oroville, Okanogan). There is one local newspaper, the Osoyoos Times.
The town’s population of 5,085 (2016) swells in the summer months with seasonal visitors. Seniors (age 65 and over) comprise 43% of the town population. Another 1,858 people live around the town within Electoral Area A of the Regional District of Okanagan-Similkameen, and 762 more in the Osoyoos 1 Indian Reserve.