LaFlamme or Laflamme is a surname. Notable people with this surname include:

Christian Laflamme (born 1976), Canadian professional ice hockey defenceman
Robert LaFlamme, American (born 1961), Author and Photographer
David LaFlamme (born 1941), American virtuoso violinist
Joseph-Clovis-Kemner Laflamme (1849–1910), Canadian Roman Catholic priest, academic and writer
Léo Kemner Laflamme (1893–1989), (American-)Canadian lawyer and politician
Lisa LaFlamme (born 1964), Canadian television journalist
Napoléon Kemner Laflamme (1865–1929), Canadian lawyer and politician
Ovide Laflamme (1925–1993), Canadian lawyer, judge and politician
Raymond Laflamme (born 1960), Canadian physicist
Rodolphe Laflamme (1827–1893), French-Canadian lawyer, professor of law and politician